منابع مشابه
The geographical spread of influenza.
How infectious diseases spread in space within one cycle of an epidemic is an important question that has received considerable theoretical attention. There are, however, few empirical studies to support theoretical approaches, because data are scarce. Weekly reports obtained since 1984 from a network of general practitioners spanning the entire French territory allows the analysis of the spati...
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Until the occurrence of the epidemic of influenza in 188990 very few living physicians knew from personal observation anything about the disease or its method of spread. They had, therefore, to rely on the teaching of the past, and I think many of them attached almost implicit reliance on the statements of Sir Thomas Watson, many of whose observations they have been able to verify in the case o...
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Although vaccines pose the best means of preventing influenza infection, strain selection and optimal implementation remain difficult due to antigenic drift and a lack of understanding global spread. Detecting viral movement by sequence analysis is complicated by skewed geographic and seasonal distributions in viral isolates. We propose a probabilistic method that accounts for sampling bias thr...
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BACKGROUND The recent emergence of hypervirulent subtypes of avian influenza has underlined the potentially devastating effects of pandemic influenza. Were such a virus to acquire the ability to spread efficiently between humans, control would almost certainly be hampered by limited vaccine supplies unless global spread could be substantially delayed. Moreover, the large increases that have occ...
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BACKGROUND Modeling plays a critical role in mitigating impacts of seasonal influenza epidemics. Complex simulation models are currently at the forefront of evaluating optimal mitigation strategies at multiple scales and levels of organization. Given their evaluative role, these models remain limited in their ability to predict and forecast future epidemics leading some researchers and public-h...
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ژورنال
عنوان ژورنال: BMJ
سال: 1951
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.4737.921